Endocrine Abstracts

Objective: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder characterised by menstrual dysfunction, infertility, presence of polycystic ovaries and biochemical and clinical hyperandrogenism affecting up to 4–18% women of reproductive age. Vitamin D is thought to influence the development of PCOS through gene transcription and hormonal modulation of insulin metabolism and fertility regulation. The aim of this prospective case–control study was to...

It is well known that adrenal masses, particularly adenomas are frequently related to metabolic syndrome and insulin resistance. However, there are no reported data about the differences between adenomas and hyperplasia.Authors examined the prevalence of symptoms of the metabolic syndrome and insulin resistance in 25 patients with adrenal incidentalomas (10 men, 15 women) of the mean age 57.9+15 years. 15 patients had adrenal adenoma determined by CT or ...

Objectives: Aim of the study was firstly to assess the prevalence of metabolic symptoms in patients with clinically silent and benign adrenal incidentalomas (AI) and secondly to determine the prevalence of C825T GNB3 gene polymorphism in AI as well as its relation to metabolic variables.Subject and methods: Group of patients consisted of 50 patients with AI of mean age 57.9±15 years and group of controls consisted of 22 subjects without AI and metab...